MicroCal Isothermal Titration Calorimeter (ITC) Isothermal Titration Calorimeter (ITC)

Model: 
Isothermal Titration Calorimeter (ITC)
Make: 
Supplier: 

Microcalorimetry measures minute heat changes associated with intra- and intermolecular interactions. It provides a rapid, direct method for determining drug or ligand-target binding affinities, without the need for radiolabelling, immobilisation, or indirect spectroscopic methods. The VP-ITC system is an ultrasensitive isothermal titration calorimeter that uses a cell feedback network (CFB) to differentially measure and compensate for heat produced or absorbed between the sample and reference cell. A major advantage of the VP-ITC system is three users-selectable modes of operation: high gain, low gain and passive. The high gain mode is suggested for most ITC experiments, allowing the fastest re-equilibration between injections, thereby providing the shortest experimental times. The passive mode has the lowest noise, and is useful when examining very small signal changes in systems having slow transients. 

Condition: 
New
Category: 
Calorimeter - Isothermal Titration Calorimeter (ITC)
Disciplines: 
Biochemistry, Biophysics
Life Expectancy: 
10years
Location
Faculty: 
Health Sciences
Department: 
Health Science
Building: 
Room 647, Level 6, Falmouth Building
University of Cape Town
Rhodes Drive
Cape Town
7701

Contact Person/s

Name: Prof EDS Sturrock
Phone: +27 21-406-6312
Email: edward.sturrock@uct.ac.za

Grantholder

Title: Prof
First Name: EDS
Last Name: Sturrock
Phone: +27 21-406-6312
Email: edward.sturrock@uct.ac.za
Funding Information
Equipment Price: 
R843,290
Year of Acquisition: 
2008